EBO3 therapy is a medically supervised procedure that circulates your blood through a sterile, closed circuit outside the body. Inside the circuit, blood passes through a filter and is exposed to a measured mix of oxygen and ozone, then returned to you. It is also called EBOO, EBO2, or ozone blood therapy.
The Longevity Center FL offers EBO3 therapy at our West Palm Beach clinic, led by Dr. Benjamin Kosubevsky, DO. Every patient starts with a consultation and a straight answer about what the research does and does not show.
| Detail | The Longevity Center FL |
|---|---|
| Price | $830 per session |
| Initial consultation | $175 |
| Session length | About one hour in the chair |
| FDA status | Not FDA approved for any condition |
| Insurance | Self-pay, no insurance billing |
| Booking | Usually one to two weeks out |
| Location | 580 Village Blvd, Suite 210, West Palm Beach, FL 33409 |
EBO3, EBOO, EBO2, and EBO all describe the same family of treatments. None is a formal medical category, and the number after the letters does not signal a different therapy.
| Term | What it usually means |
|---|---|
| EBOO | Extracorporeal blood oxygenation and ozonation. This is the name used in the published research. |
| EBO2 | A common variant. Clinics and equipment sellers often use it for higher-volume setups. |
| EBO3 | The newest label, generally used for equipment with more adjustable settings. Examples include separate oxygen and ozone controls, light options in the circuit, and larger blood volumes. Some clinics also use it as the name of their own protocol. |
| EBO | Shorthand for the whole category. |
Because the labels are not standardized, the name on a clinic’s website tells you very little. These questions tell you much more:
Ask them anywhere you are considering treatment, including here.
EBO3 pairs an external blood circuit, similar to the setup used in dialysis, with a controlled mix of oxygen and ozone.
An IV line is placed in each arm. Blood is drawn from one arm and pumped through a sterile, single-use circuit and filter. It returns through the other arm in a continuous loop. An anticoagulant (blood thinner) keeps blood from clotting in the circuit, and the tubing and filter are discarded after every session.
When ozone meets blood, it reacts with antioxidants and other molecules in plasma. Researchers propose that this controlled oxidative challenge triggers a stress response, with immune and endothelial cells as proposed targets (Di Paolo et al., 2005a).
The same group measured a four- to fivefold rise in a lipid oxidation marker after a session. Plasma protein thiols fell by a matching amount, with no appreciable hemolysis (breakdown of red blood cells).
Research on ozone and human blood describes a hormetic dose-response: low and high doses act very differently, and too much is harmful (Bocci et al., 2011). That is why our providers treat ozone concentration as a clinical decision, not a default machine setting.
| Feature | Traditional ozone IV (autohemotherapy) | EBOO / EBO3 |
|---|---|---|
| How blood is treated | One batch is drawn, mixed with ozone, and returned | Blood circulates continuously through an external circuit |
| Blood treated | Only about 250 mL | Up to 4,800 mL in one hour with the original research apparatus |
| IV lines | One | Two, one in each arm |
Volumes are from Di Paolo et al., 2005a. The volume in any given session depends on the equipment and protocol. For more, see our IV Ozone Therapy page and our breakdown of EBOO vs. traditional ozone therapy.
EBO3 at our clinic follows a sequence built around measuring before and after.
We don’t guess, we test.
EBO3 is not appropriate for everyone. Your provider makes the final call after reviewing your full history, medications, and recent labs.
Screening pays close attention to:
Because the circuit uses an anticoagulant and needs an IV line in each arm, bleeding risk and vein access are part of every screening. If you have a medical condition, list it on your intake forms. Your provider will decide whether EBO3 or a different approach is the right place to start.
EBO3 therapy at The Longevity Center FL in West Palm Beach costs $830 per session. The initial consultation is $175.
They describe the same family of treatments: extracorporeal blood oxygenation and ozonation. EBOO is the name used in the research, and EBO3 is a newer label usually tied to equipment with more adjustable settings.
Not by name alone. The labels are not standardized, so ozone concentration, blood volume, screening, and medical oversight matter far more than the number.
Safety depends on screening, equipment, dosing, and supervision. Possible side effects include bruising or soreness at the IV sites, lightheadedness, and fatigue. The anticoagulant used in the circuit also adds bleeding risk. Your provider reviews all known risks with you during informed consent.
Traditional IV ozone (autohemotherapy) treats one batch of about 250 mL of blood. EBO3 circulates blood continuously through an external circuit, so it can treat a much larger volume in one session.
An EBO3 session at The Longevity Center FL takes about one hour in the chair. Plan for extra time for IV placement and a check before you leave.
Your care team gives you instructions before your visit, including guidance on hydration and eating beforehand. Bring a current list of your medications and supplements.
The main discomfort is usually the IV placement, one in each arm. Tell your care team right away if anything feels off during the session.
EBO3 therapy at The Longevity Center FL costs $830 per session. The initial consultation is $175.
No. The Longevity Center FL is self-pay for all services. Ask your HSA or FSA administrator whether EBO3 is an eligible expense.
The Longevity Center FL is at 580 Village Blvd, Suite 210, West Palm Beach, FL 33409. We see patients from throughout Palm Beach County.
Before you book EBO3 anywhere, talk to a licensed medical provider who will test first and tell you plainly what to expect. Schedule a consultation with our West Palm Beach team.
We don’t guess, we test.
This page is for education and is not medical advice. Decisions about EBO3 therapy should be made with a licensed medical provider.
Schedule your appointment today and take the first step toward a healthier, more balanced life.
Schedule an Appointment