Temporomandibular joint (TMJ) pain and dysfunction often involve micro-instability, mild joint degeneration, ligament laxity, or soft tissue irritation around the jaw hinge. In appropriate candidates, prolotherapy (injection of a proliferant such as hypertonic dextrose) or tissue allograft injections (e.g. biologic matrix/allograft preparations) can stimulate a reparative cascade in and around the joint and ligaments.
These therapies are intended to complement conservative approaches (physical therapy, occlusal adjustment, soft-tissue work) and are not a substitute for surgical or emergent interventions.
Targeted injection: We precisely deliver the proliferant or biologic allograft to the ligaments, joint capsule, or periarticular tissue around the TMJ.
Healing cascade initiation: The injected solution (e.g. dextrose) triggers a mild inflammatory response (controlled microtrauma) that signals your body to send repair cells, collagen, and vascular ingrowth to the area.
Remodeling and stabilization: Over weeks to months, ligament tissue may strengthen, collagen reorganizes, and micro-instability can reduce. The allograft matrix may assist in providing a scaffold to direct better tissue organization.
Symptom reduction & function: As the tissues stabilize, pain, joint clicking, and muscular guarding often lessen. Some patients regain improved range of motion, less jaw fatigue, and better chewing comfort.
It’s important to understand: regeneration is not instantaneous, and multiple sessions may be needed. Outcomes depend on patient factors (age, tissue health, mechanical stress, dental alignment).
While results vary, some of the commonly reported benefits include:
We aim for functional improvement rather than overpromising cure. We cannot guarantee specific results in all cases.
You may be a candidate if you:
Contraindications / cautionary flags include: active joint infection, malignancy, severe uncontrolled systemic illness, bleeding disorders, or allergy to components of the injection. All patients are screened carefully for appropriateness.
| Phase | What Happens | Typical Duration |
|---|---|---|
| Initial consultation & imaging | We review your TMJ history, imaging (MRI/CBCT), exam findings, and plan injection targets and protocol | 15-30 min |
| Injection session | Local anesthesia, sterile preparation, ultrasound/fluoro guidance, injection of proliferant/allograft | ~30 min |
| Post-procedure | Mild soreness/swelling for 24–72 hours, soft diet, ice, limited jaw use | 2–3 days |
| Follow-up & rehab | Gentle jaw mobilization, physical therapy, bite stabilization, assessments | Weeks to months |
| Repeat sessions | Often 2–4 injections spaced over 4–8 weeks, depending on response | Up to 3–4 months |
You’ll likely begin noticing changes in 4–6 weeks, with continued improvement over 3–6 months. Some residual effect may persist beyond that in favorable responders.
We employ strict sterile technique and imaging guidance to maximize safety. Common mild side effects may include:
If you live with TMJ-related jaw pain, clicking, or instability, and are seeking options beyond standard care, this regenerative approach may be a solution. During your consultation, we’ll:
Schedule your appointment today to explore whether TMJ Prolotherapy or Tissue Allograft Injection is right for your jaw health and long-term function.
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