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PRP Side Effects & Recovery: What You Should Know

A woman lays in a chair with her eyes closed. Someone stands next to her with a syringe and vial of blood.

April 2, 2025; By admin

Platelet-rich plasma (PRP) therapy generates buzz for its ability to harness your body’s natural healing abilities. Whether you’re looking to smooth out fine lines, encourage hair growth, or address an old scar, PRP can address these concerns without relying on chemicals or surgery. But like any treatment, it’s important to fully understand the process. This guide breaks down everything you should know about PRP side effects and recovery.

How PRP Works: The Science Behind It

PRP therapy centers around your blood. Platelets are proteins that stimulate your body’s natural healing. Plasma acts as a carrier, delivering these components to tissues that need repair.

The success of PRP lies in its preparation. A healthcare provider draws a small amount of blood. They will place the blood in a centrifuge. The rapid spinning separates the layers of blood, isolating the platelets and plasma while removing red and white blood cells. This process produces a concentrated solution rich in growth factors, specifically tailored to maximize therapeutic benefits.

Custom Applications, Same Natural Process

PRP injections use the body’s natural substances rather than external chemicals or synthetic materials, appealing to people seeking natural remedies. For example, in hair restoration, PRP reactivates dormant follicles to encourage new hair growth and improve the hair’s thickness. Since the therapy uses your blood, it eliminates the risk of rejection, making the treatment safe and effective.

Specific Types of PRP Treatments

PRP treatments can help with a variety of concerns. Here are a few specific treatment options:

  • PRP facials and microneedling rejuvenate the skin by boosting collagen production and speeding up healing. This treatment reduces wrinkles, tightens skin, improves texture, and lightens minor scars.
  • PRP for hair restoration reactivates dormant hair follicles, promoting thicker, fuller hair and increasing hair volume. It’s ideal for addressing early hair thinning.
  • PRP for scar reduction lightens scars by breaking down fibrous tissue and stimulating healthy skin regeneration. This treatment smooths skin, evens discoloration, and lessens scar visibility by targeting the skin’s surface and deep layers.
  • PRP for sexual health can benefit males and females. For men, it improves circulation and sexual performance. For women, it relieves vaginal dryness and sensitivity to restore comfort.

A close-up of a medical professional injecting a syringe in a man's scalp. The man has brown hair with a bald patch.

Common Side Effects of PRP Treatments

Something you should know about PRP side effects is that treatments may leave the treated area slightly inflamed, which is a sign that healing is underway. Swelling, redness, and minor tenderness are common and short-lived symptoms. These effects usually peak within the first 24 to 48 hours, with a noticeable decrease after this time frame.

Mild discomfort is another common side effect, and you might feel a dull ache or soreness at the injection site. These sensations usually resolve quickly and don’t interfere with normal daily activities. Moreover, bruising can appear around injection sites, particularly in areas with thin skin or high vascularity.

While you should expect these effects, pay attention to symptoms that seem unusual. Excessive swelling or bruising that worsens over several days could indicate the need for further evaluation. Always reach out to your provider if you feel out of the ordinary.

Rare but Serious Risks To Be Aware Of

Infections can happen if the injection site isn’t sterile or if you fail to follow aftercare instructions. To reduce the risks of infection, choose a clinic that follows strict hygiene protocols. While allergic reactions are rare, disclosing your medical history and any skin sensitivities is essential. This allows your provider to take precautions and minimize potential irritation during treatments.

Though serious complications are uncommon, symptoms like severe pain, excessive swelling, or fever require immediate medical attention. Watch for signs like increased pain, warmth, or pus at the site, and contact your provider immediately if they occur. It’s best to follow all pretreatment and posttreatment instructions carefully.

PRP Recovery Timeline and What To Expect

Healing differs depending on the PRP treatment you receive. Here’s an overview of recovery timelines based on the procedure.

PRP Facials and Microneedling

After PRP facials and microneedling, the skin may turn red and swell slightly during the first 24 to 48 hours, resembling a mild sunburn. During this period, avoid applying makeup or touching your face excessively.

Between days three and five, your skin starts peeling lightly as it renews itself, so stick to hydrating skincare and avoid exfoliating products. By the end of the first week, redness fades. The skin feels smoother and appears more radiant. Full results commonly appear between four and six weeks.

PRP Scar Reduction

If you receive a PRP scar reduction procedure, treated areas may feel red, warm, or slightly swollen for the first 24 hours. Between days two and five, tenderness decreases as skin regeneration begins.

While scars may appear redder initially, noticeable improvements in texture and appearance usually start by the second week. Full benefits take three to six months to develop as collagen rebuilds and reduces scarring. Treat the area gently during this time by avoiding scrubbing or harsh skincare products.

PRP for Sexual Health

With PRP treatments for male and female sexual health, you may experience slight discomfort at the injection site for the first 24 to 48 hours. Mild sensitivity or swelling may linger for a few days, but it will resolve quickly. You may notice subtle improvements in function and sensitivity by the second week, with peak results appearing six to eight weeks later.

PRP Hair Restoration

For PRP hair restoration, the scalp may feel tender; you might notice minor redness or swelling. Avoid washing your hair or applying products for at least 24 hours. To care for your scalp, avoid direct sun exposure and refrain from coloring or treating your hair for at least a week following the treatment.

By days two to five, residual soreness usually subsides, allowing you to return to your normal haircare routine. Hair shedding may temporarily increase between the second and fourth week as the hair growth cycle resets. New hair growth generally starts between three and six months, with optimal results becoming visible six to twelve months following treatment.

Tips for Maximizing PRP Results

Follow these key steps to enhance your PRP treatment outcomes:

  • Prepare for the session by staying hydrated and avoiding anti-inflammatory medications 48 hours prior to the procedure, as the medications can interfere with platelet activity.
  • Protect the treated area by using gentle products, avoiding sunlight, and steering clear of irritants like harsh shampoos or tight garments.
  • Stick to your treatment schedule by completing all recommended sessions to achieve the best results.
  • Track your progress by documenting improvements, consulting your provider for adjustments, and requesting additional treatments, if needed.

A smiling woman sits in a chair and touches her face while looking in a mirror. A doctor wearing a mask stands behind her.

Your Journey to Rejuvenation Starts Here

At The Longevity Center FL, we’re passionate about helping our clients feel and look their best. Whether restoring your skin’s glow or encouraging fuller hair, we offer treatments that complement the body’s natural healing process.

Are you curious about how PRP treatments can help? Book a consultation today. Let’s work together to achieve the confidence and wellness you deserve!