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How Long Do Regenerative Injections Last?

A close-up of gloved hands injecting PRP treatment into a patient's knee. The person elevates their other knee.

July 29, 2025; By Benjamin Kosubevsky

Living with chronic pain or recovering from an injury can interrupt daily life. Regenerative injections attract a lot of attention because they promote natural healing instead of covering symptoms. But how long do regenerative injections last? Let’s evaluate this treatment option to determine if it aligns with your needs and goals for lasting relief.

What Are Regenerative Injections?

Regenerative injections encourage the body’s natural healing processes. Instead of masking symptoms, these treatments target the underlying causes of pain or injury and help repair damaged tissue. The treatment appeals to many people, especially those who deal with chronic conditions like arthritis, tendon injuries, or joint degeneration.

These therapies rely on substances naturally found in your body, such as platelets or cells from bone marrow. Providers use advanced techniques to extract and concentrate these materials before injecting them into the affected area. The concentrated components then trigger your body to rebuild and restore damaged tissue.

For instance, say you have chronic knee pain due to cartilage wear. Traditional treatments might include medications for pain relief or physical therapy. Orthobiologic injections like platelet-rich plasma (PRP) or bone marrow aspirate concentrate (BMAC) could offer a targeted, less-invasive alternative to stimulate healing.

PRP therapy separates platelets from your blood and injects the concentrated solution into the injury site. Platelets deliver growth factors, which encourage tissue repair and regeneration. PRP works well for people with joint injuries, arthritis, or ligament tears. This treatment reduces inflammation and alleviates pain in soft tissue injuries.

Providers use BMAC therapy to extract mesenchymal stem cells from your bone marrow and inject them into damaged areas. These cells transform into various tissue types, including cartilage, bone, and tendons, to aid repair. BMAC benefits individuals dealing with joint deterioration, such as osteoarthritis or cartilage loss.

Prolotherapy treats ligament and tendon injuries by injecting a natural irritant, such as dextrose, into the affected area. This irritant activates the body’s healing response, forcing the injured area to repair itself. Prolotherapy serves individuals managing chronic joint instability, back pain, or ligament damage. Over multiple sessions, it strengthens and stabilizes the area.

Understanding Treatment Length

Many wonder how long regenerative injections last, especially compared to traditional treatments. However, the duration of relief depends on several factors, including the injection type, the condition being treated, and your body’s response to the therapy. For more insights, here’s a breakdown of each factor.

1. Type of Injection

Different injections have varying durations. For example, PRP injections last between six months to a year. BMAC treatments may provide relief for over a year or longer. Meanwhile, prolotherapy may require multiple sessions to see long-term results.

2. Condition Treated

The condition you’re treating also plays a big role. For joint conditions like mild arthritis, PRP may produce results that last six to nine months. More advanced conditions could require additional sessions to maintain relief. Chronic injuries, such as tendon tears, may require fewer treatments, as they often heal completely after one or two sessions.

3. Individual Factors

Each person’s body heals differently. Your age, activity level, and overall health can impact how long the effects last. For example, younger individuals and those with healthier lifestyles may respond better to these treatments compared to those managing multiple health conditions. An older individual with advanced arthritis might require more sessions or various types of regenerative injections.

A practitioner holds a vial of blood, and a woman sits in the treatment chair. The woman smiles and wears a robe.

Potential Side Effects

Regenerative injections are safe and use your body’s own materials, which lowers the risk of complications. You may notice minor side effects like swelling, redness, or tenderness at the injection site, but these symptoms usually fade within a few days as your body heals.

Rarely, infections or nerve irritation can occur, but you can reduce these risks by choosing a skilled provider who follows strict sterilization practices. Contact your provider if you experience prolonged pain, major swelling, or signs of infection.

Questions To Ask Your Provider

Before undergoing regenerative injection treatments, you should ask your provider questions to feel informed and confident about your care. Here’s a list of questions to consider:

  • What type of regenerative injection do you recommend for my condition and why?
  • How many sessions will I need, and how long does it typically take to see results?
  • What steps should I take to prepare for my injection?
  • What can I do after the treatment to maximize its effectiveness?
  • What kind of posttreatment care or activity restrictions should I expect?

Lifestyle Changes To Support Healing After Injections

Although your provider may recommend specific posttreatment plans, you can support recovery with effective lifestyle changes. Consume nutrient-dense foods that promote tissue repair, such as leafy greens, lean proteins, and foods high in omega-3 fatty acids. Avoid processed or sugary foods that can contribute to inflammation and slow healing.

Exercise also helps, but you must tailor your activity level to your recovery stage. Light stretching or low-impact exercises like swimming or yoga can improve circulation and prevent stiffness as you heal. Over time, your provider may recommend introducing strength-building exercises to support the treated area.

Lastly, you should establish habits that reduce stress, as stress can limit the body’s ability to recover efficiently. Practices like meditation, deep-breathing exercises, or short walks can do wonders for your mental and physical well-being.

How To Monitor Your Progress After Treatment

Tracking your recovery after regenerative injections will help you notice improvements and stay informed about your healing. Document changes in pain levels, mobility, or day-to-day function. This practice helps you track patterns and pinpoint how the treatment impacts your condition over time.

Pay close attention to shifts in your ability to perform activities that were challenging before treatment. Whether it’s walking up a flight of stairs or gripping objects without discomfort, these small yet substantial signs indicate progress. Communicating these observations with your provider also offers valuable insights for your ongoing care.

Frequent follow-ups with your health care provider also help monitor progress. Providers may use imaging tests, like MRIs or X-rays, to assess tissue growth and healing. These updates confirm whether the treatment meets your goals or if you need additional injections.

A man lies on a table as a practitioner lifts his leg and bends his knee. The practitioner wears a gray T-shirt.

Heal From Within at The Longevity Center FL

If you’re living with pain or struggling to find relief, we’re here to help. At the Longevity Center FL, we understand how exhausting it can feel to search for solutions that truly work. Using advanced regenerative therapies, we can address the root cause of your pain rather than just managing the symptoms. Our team works with you every step of the way, creating a plan that prioritizes your healing, comfort, and long-term well-being. Start your healing journey today.

Benjamin Kosubevsky

Meet Dr. Benjamin Kosubevsky

Dr. Benjamin Kosubevsky is a board-certified expert in regenerative and integrative medicine. He’s developed his own Ozone Dialysis (EBOO) protocols for more effective, lasting results. With training from leading organizations in ozone, stem cell, and chelation therapies, he offers advanced treatments like PRP, BMAC, and OMT. Dr. Kosubevsky blends traditional and holistic care to create personalized plans that support natural healing. He also co-hosts the Peak Performance Podcast, where he shares insights on health, recovery, and optimal living.